Fifteen minutes into practice, while everyone has
warmed up, youre winded. Could be youre just plain out of condition
or
it could be that, like 10 % of the gold medal winners in the 1984 Olympics, you have
exercise-induced asthma. Forty percent of those with allergic rhinitis (inflammation of
the nasal mucous membranes) and 12% of the general population have exercise-induced
asthma.
Usually people with exercise-induced asthma experience shortness of breath after 10-15
minutes of exercise. If they work through it they get better and may be symptom-free for
about four hours. The diagnosis is made by checking pulmonary function tests or a peak
flow after exercise. A drop in peak flow of greater than 10% gives you a diagnosis of
exercise-induced asthma.
The treatment has traditionally been to use an albuterol inhaler 20
minutes before exercise. For athletes involved in long tournaments or activities, however,
this may require multiple dosing during the event. Another alternative has been cromolyn.
Unfortunately, only 30% of people respond to
cromolyn.
In a recent article in the New England Journal of Medicine, salmeterol (Serevent)
was shown to maintain protection against exercise-induced asthma even after a month. There
was a reduction in the decrease of FEV1 by around 10%. Salmeterol is a long lasting form
of albuterol.
In that same issue of the New England Journal of Medicine, a new type of medication,
montelukast
(Singulair), was shown to work well in exercise-induced asthma. The outcome that was
examined was the area under the curve of the change in FEV1 in the first 60 minutes after
exercise. Simply put, they were looking at how well the montelukast prevented a drop in
lung function. There was a 47.4% reduction in the area under the curve. There was also a
significant benefit in a lower maximal decrease in lung function and a shorter return of
lung function to baseline. Tolerance to the medication (where it doesnt work
anymore) and rebound (where things are worse after stopping the medicine) was not seen.
Seventy three percent of the patients felt that they were better. Side effects were no
different than a placebo. Montelukast can be used in children as young as five years
old.
So for those of you who poop out with exercise or cough with exercise, see your doctor.
If you have exercise-induced asthma, you may benefit from albuterol. If the albuterol
doesnt last long enough or if you develop tolerance to it, perhaps you might benefit
from salmeterol or montelukast. If youre just out of condition, keep at it, it
eventually gets easier.